Pharmacokinetic-Pharmacodynamics Senior/Principal Scientist

Job Listing No: 9740000

Pharmacokinetic-Pharmacodynamics Senior/Principal Scientist

Zoetis is a global animal health company dedicated to supporting customers and their businesses in ever better ways. Building on 60 years of experience, we deliver quality medicines and vaccines, complemented by diagnostic products and genetic tests and supported by a range of services. We are working every day to better understand and address the real-world challenges faced by those who raise and care for animals in ways they find truly relevant.Our name, Zoetis (z-EH-tis), has its root in zo, familiar in words such as zoo and zoology and derived from zoetic, meaning “pertaining to life.” It signals our company”s dedication to supporting the veterinarians and livestock producers everywhere who raise and care for the farm and companion animals on which we all depend.Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.Position SummaryZoetis is the largest animal health company in the world with an industry-leading research and development team. We are seeking a talented senior pharmacokinetics-pharmacodynamics scientist to join our research and development team to develop novel veterinary therapies. This position will require a highly motivated and independent leader who can effectively collaborate with other team members to advance projects. The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK/PD studies in multiple species in support of projects from early research through late-stage development. Responsibilities* Independently design, conduct and analyze data for in vivo TK, PK and PK/PD studies in multiple veterinary species for large molecule and/or small molecule therapeutics* Provide PK and PK/PD modeling and simulation to help select lead candidates and optimize dose regimens* Serve as study director or principal investigator for in vivo PK, PK/PD or TK studies (GLP and non-GLP), including writing protocols and reports.* Work collaboratively with interdisciplinary teams to prosecute studies and projects in line with the strategic direction of the team* Present results to scientific teams, management, and regulatory agencies* Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents* Mentor other scientists Minimum Qualifications* PhD in Pharmacology, Biochemistry, or related discipline with a minimum of 4 years of industry experience in PK/PD of small or large molecules, or a BS/MS with a minimum of 8 years of relevant industry experience.* Demonstrated ability to design, analyze and interpret in vivo PK and PK/PD studies.* Skilled in the used of PK and PK/PD modeling and simulation software such as WinNonlin, NONMEM, etc.* Highly independent with the ability to innovate within the discipline* Excellent written and oral communication skills* Working knowledge of analytical methodology for large molecule and small molecule analyses, including ligand binding assays (immunoassays) and LC/MS/MS assays. Desirable Skills* Experience conducting GLP regulated studies* Experienced with monitoring work at CROs* Experience developing population PK models and/or evaluating PK variance in clinical populations* Experience with radiolabeled (14C and/or 3H) drug disposition studies* Experienced with LIMS software, such as Watson.

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