Sr. Fermentation Scientist I, San Diego
At BASF, we create chemistry through the power of connected minds. By balancing economic success with environmental protection and social responsibility, we are building a more sustainable future through chemistry. As the world s leading chemical company, we help our customers in nearly every industry meet the current and future needs of society through science and innovation.We provide a challenging and rewarding work environment and are always working to form the best team especially from within, through an emphasis on lifelong learning and development.And we are constantly striving to become an even better place to work. BASF has been recognized by Forbes Magazine as one of America s Best Employers in 2016. Come join us on our journey to create solutions for a sustainable futureWhere the Chemistry HappensBASF Enzymes LLC in San Diego is seeking a hardworking, technically proficient, enthusiastic Bioprocess Development Fermentation Scientist to lead the development of industrial enzyme fermentation processes from laboratory scale to commercial scale (50,000L plus). Bioprocess Development Fermentation Scientist (1602803) You will work in a dynamic, cross-functional team to design scalable fermentation processes, transfer processes to Pilot Plant and commercial scale, and employ continuous improvement strategies to enhance productivity, reduce cost of goods, and troubleshoot manufacturing issues as they arise. This position offers the opportunity to work in a global multidisciplinary team in a challenging and dynamic environment. Formula for Success: You Will Understanding of safety requirements and their implementationDevelop aerobic fermentation processes for recombinant enzymes, expressed in bacterial, yeast and fungal hosts, in collaboration with downstream processing subject matter experts, to maximize enzyme yields and reduce cost of goodsDevelop procedures (SOPs) and supervising microbial fermentations for producing enzymes in support of regulatory submissions at pilot scale (EPA, FDA, food cGMPs)Lead the fermentation process development, scale-up and process transfer to tollers and commercial manufacturing partnersDevelop and refine of scaledown models to strengthen commercial scale predictability at lab and pilot scalesProvide troubleshooting support for commercial manufacturing operations, and performing continuous improvement studies for existing commercial processes Work within multidisciplinary project teams which include EH&S, Research, Quality, Regulatory, Engineering and Manufacturing teams to design and execute fermentation optimization campaigns, interpreting data, and working with other team members to integrate results into process designs and overall project plans Provide significant contributions to the BASF Enzymes Pilot Plant operation and development efforts with respect to training and data archival, management, and presentationCreate Your Own Chemistry: What We Offer YouAdding value to our customers begins with adding value to you. You@BASF is the suite of benefits, perks, programs and unique opportunities we offer to support you the whole you in all stages of your life and career. With you@BASF, you create your own chemistry.The total rewards that you receive as a BASF employee go way beyond a paycheck. From competitive health and insurance plans, to robust retirement benefits that include company-matching contributions, to making sure you never stop learning, we believe investing in you is investing in our success. Working for a large, global organization, you ll have a chance to grow professionally and personally, expand your network and build a rewarding and dynamic career.Ingredients for Success: What We Look For in YouPhD in chemical/biochemical engineering or another related technical discipline and minimum 2+ year of relevant industrial experience, OR Master s Degree in chemical/biochemical engineering or another related technical discipline with minimum 5+ years of relevant industrial experience, OR BS chemical/biochemical engineering or another related technical discipline and minimum 7+ years relevant industrial experience is required. Experience in industrial fermentation scale-up, scaledown and/or process modeling with internal and external partners is requiredStrong technical background and direct hands-on experience with pilot and/or commercial scale fermentation processes is requiredDirect experience in industrial enzymes fermentation development is preferredUnderstanding of protein biochemistry, microbiology and recombinant protein expression in microbial hosts is preferredBasic understanding of process design within regulatory guidelines (e.g. food/feed cGMPs) is preferredWorking knowledge and experience in downstream processing unit operations such as continuous centrifugation, tangential flow filtration and normal flow filtration is preferredApply for this job.